Gastrointestinal (GI) Infections

GenMark is committed to expanding its menu of multiplex molecular panels to address a wide variety of clinical needs in the area of gastrointestinal (GI) infections. The following information is provided as an educational resource only.

WHAT ARE GI INFECTIONS?
GI infections are caused by the ingestion of harmful pathogens, such as bacteria, viruses or parasites, into the digestive tract. These infections are often spread through contaminated food or water, but can also spread person-to-person due to poor hygiene. Most people with GI infections recover on their own, but GI infections can be dangerous in persons with weakened or compromised immune systems.

HOW PREVALENT ARE GI INFECTIONS?
GI infections cause a significant infectious disease burden worldwide, with approximately 3-5 billion cases of diarrheal disease and mortality of 1.4 million annually.1 While GI infections are common in both resource-rich and less developed countries, they are associated with different risk factors. In developing countries, illness is often linked to sanitation related factors, but in developed countries GI infections are more often foodborne, and associated with seasonal prevalence, and travel.2  The CDC estimates that each year roughly 1 in 6 Americans (or 48 million people) get sick, 128,000 are hospitalized, and 3,000 die of foodborne illnesses.3

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References:
1. World Health Organization. (2013). Diarrheal Disease Fact Sheet 330. http://www.who.int/mediacentre/factsheets/fs330/en/
2. Fletcher, S., et al. (2013). Prevalence of gastrointestinal pathogens in developed and developing
countries: systematic review and meta-analysis. J Public Health Res. 2(1): 42–53.
3. http://www.cdc.gov/foodborneburden/ (accessed February 2016)

*Product in development. Not available for sale in the US. Specifications subject to change.